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Cold Spring Harbor Symposia on Quantitative Biology. v. 73, Control and regulation of stem cells / meeting organized by Bruce Stillman, David Stewart and Terri Grodzicker. — Woodbury, N.Y. : Cold Spring Harbor Laboratory Press, 2008. – (58/C688/v.73)

Contents

    Contents
    
    Symposium Participants
    Foreword
    
    Germ Cells and Totipotency
    Regulating Gene Expression in the Drosophila Germ Line
    Germ Line, Stem Cells, and Epigenetic Reprogramming
    Brief History, Pitfalls, and Prospects of Mammalian Spermatogonial Stem Cell Research
    Spermatogenic Stem Cell System in the Mouse Testis
    Reprogramming and Differentiation in Mammals: Motifs and Mechanisms
    
    Niches and Asymmetry
    Interactions between Stem Cells and Their Niche in the Drosophila Ovary
    Stem Cells and Their Niches: Integrated Units That Maintain Drosophila Tissues
    Wnt Signaling and Stem Cell Control
    Niche Required for Inducing Quiescent Stem Cells
    Asymmetric Division and Stem Cell Renewal without a Permanent Niche: Lessons from Lymphocytes
    Modeling Stem Cell Asymmetry in Yeast
    
    Embryonic Development and Multipotent Progenitors
    The Maternal to Zygotic Transition in Animals and Plants
    Directed Differentiation of Pluripotent Stem Cells: From Developmental Biology to Therapeutic Applications
    Regulation of Stem Cells in the Zebra Fish Hematopoietic System
    Pioneer Factors, Genetic Competence, and Inductive Signaling: Programming Liver and Pancreas Progenitors from the Endoderm
    Generation of Cardiomyocytes from New Human Embryonic Stem Cell Lines Derived from Poor-quality Blastocysts
    Regulation of Self-renewal and Differentiation in Adult Stem Cell Lineages: Lessons from the Drosophila Male Germ Line
    
    Reprogramming Somatic Cells
    Reprogramming of Somatic Cell Identity
    Induced Pluripotency of Mouse and Human Somatic Cells
    Ronin and Caspases in Embryonic Stem Cells: A New Perspective on Regulation of the Pluripotent State
    Common Themes of Dedifferentiation in Somatic Cell Reprogramming and Cancer
    Pathways to New β Cells
    Gene Expression and Transcriptional Networks
    Mapping Key Features of Transcriptional Regulatory Circuitry in Embryonic Stem Cells
    The Transcriptional Network Controlling Pluripotency in ES Cells
    Transcriptional Regulatory Networks in Embryonic Stem Cells
    Toward Stem Cell Systems Biology: From Molecules to Networks and Landscapes
    An Unexpected Role of TAFs and TRFs in Skeletal Muscle Differentiation: Switching Core Promoter Complexes
    Sternness Is Only a State of the Cell
    
    Epigenetics
    Stem Cell Factors in Plants: Chromatin Connections
    Genetic and Epigenetic Regulation of Stem Cell Homeostasis in Plants
    Regulation of Stem Cell Differentiation by Histone Methyltransferases and Demethylases
    Epigenetic Inheritance and Reprogramming in Plants and Fission Yeast
    A Novel Epigenetic Mechanism in Drosophila Somatic Cells Mediated by PIWI and piRNAs
    Small RNA Silencing Pathways in Germ and Stem Cells
    
    Adult Stem Cells
    Epithelial Stem/Progenitor Cells in Lung Postnatal Growth, Maintenance, and Repair
    Multipotent Islet-1 Cardiovascular Progenitors in Development and Disease
    Regulation of Skeletal Muscle Stem Cell Behavior by Pax3 and Pax7
    Regulation and Function of Skeletal Muscle Stem Cells
    The Molecular Regulation of Muscle Stem Cell Function
    Building Epithelial Tissues from Skin Stem Cells
    Very Long-term Self-renewal of Small intestine, Colon, and Hair Follicles from Cycling Lgr5+ve Stem Cells
    
    Neural Stem Cells and Brain Tumors
    The Heterogeneity of Adult Neural Stem Cells and the Emerging Complexity of Their Niche
    Notch, Neural Stem Cells, and Brain Tumors
    Human ESC-derived Neural Rosettes and Neural Stem Cell Progression
    Metabolomics of Neural Progenitor Cells: A Novel Approach to Biomarker Discovery
    Signaling Pathways Controlling Neural Stem Cells Slow Progressive Brain Disease
    Cancer Stem Cells in Brain Tumor Biology
    Neural and Cancer Stem Cells in Tumor Suppressor Mouse Models of Malignant Astrocytoma
    Pten and p53 Converge on c-Myc to Control Differentiation, Self-renewal, and Transformation of Normal and Neoplastic Stem Cells in Glioblastoma
    
    Stem Cells and Cancer
    Establishment of a Normal Hematopoietic and Leukemia Stem Cell Hierarchy
    Role of "Cancer Stem Cells" and Cell Survival in Tumor Development and Maintenance
    The 1NK4-ARF (CDKN2A/B) Locus in Hematopoiesis and BCR-ABL induced Leukemias
    Delineating the Epithelial Hierarchy in the Mouse Mammary Gland
    Stem Cell Biology in the Lung and Lung Cancers: Using Pulmonary Context and Classic Approaches
    Epithelial Stem Cells of the Prostate and Their Role in Cancer Progression
    Role of β-catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
    Implications of Cellular Senescence in Tissue Damage Response, Tumor Suppression, and Stem Cell Biology
    
    Renewal and Regeneration
    Regulation of Self-renewal and Differentiation in the Drosophila Nervous System
    Progenitor Cells for the Prostate Epithelium: Roles in Development, Regeneration, and Cancer
    Stem Cells Use Distinct Self-renewal Programs at Different Ages
    Complementary and Independent Function for Hoxb4 and Bmil in HSC Activity
    Regeneration, Stem Cells, and the Evolution of Tumor Suppression
    Germ Cell Specification and Regeneration in Planarians
    Novel Insights into the Flexibility of Cell and Positional Identity during Urodele Limb Regeneration
    Summary: Present and Future Challenges for Stem Cell Research
    Author Index
    Subject Index