Cold Spring Harbor Symposia on Quantitative Biology. v. 73, Control and regulation of stem cells / meeting organized by Bruce Stillman, David Stewart and Terri Grodzicker. — Woodbury, N.Y. : Cold Spring Harbor Laboratory Press, 2008. – (58/C688/v.73) |
Contents
Contents
Symposium Participants
Foreword
Germ Cells and Totipotency
Regulating Gene Expression in the Drosophila Germ Line
Germ Line, Stem Cells, and Epigenetic Reprogramming
Brief History, Pitfalls, and Prospects of Mammalian Spermatogonial Stem Cell Research
Spermatogenic Stem Cell System in the Mouse Testis
Reprogramming and Differentiation in Mammals: Motifs and Mechanisms
Niches and Asymmetry
Interactions between Stem Cells and Their Niche in the Drosophila Ovary
Stem Cells and Their Niches: Integrated Units That Maintain Drosophila Tissues
Wnt Signaling and Stem Cell Control
Niche Required for Inducing Quiescent Stem Cells
Asymmetric Division and Stem Cell Renewal without a Permanent Niche: Lessons from Lymphocytes
Modeling Stem Cell Asymmetry in Yeast
Embryonic Development and Multipotent Progenitors
The Maternal to Zygotic Transition in Animals and Plants
Directed Differentiation of Pluripotent Stem Cells: From Developmental Biology to Therapeutic Applications
Regulation of Stem Cells in the Zebra Fish Hematopoietic System
Pioneer Factors, Genetic Competence, and Inductive Signaling: Programming Liver and Pancreas Progenitors from the Endoderm
Generation of Cardiomyocytes from New Human Embryonic Stem Cell Lines Derived from Poor-quality Blastocysts
Regulation of Self-renewal and Differentiation in Adult Stem Cell Lineages: Lessons from the Drosophila Male Germ Line
Reprogramming Somatic Cells
Reprogramming of Somatic Cell Identity
Induced Pluripotency of Mouse and Human Somatic Cells
Ronin and Caspases in Embryonic Stem Cells: A New Perspective on Regulation of the Pluripotent State
Common Themes of Dedifferentiation in Somatic Cell Reprogramming and Cancer
Pathways to New β Cells
Gene Expression and Transcriptional Networks
Mapping Key Features of Transcriptional Regulatory Circuitry in Embryonic Stem Cells
The Transcriptional Network Controlling Pluripotency in ES Cells
Transcriptional Regulatory Networks in Embryonic Stem Cells
Toward Stem Cell Systems Biology: From Molecules to Networks and Landscapes
An Unexpected Role of TAFs and TRFs in Skeletal Muscle Differentiation: Switching Core Promoter Complexes
Sternness Is Only a State of the Cell
Epigenetics
Stem Cell Factors in Plants: Chromatin Connections
Genetic and Epigenetic Regulation of Stem Cell Homeostasis in Plants
Regulation of Stem Cell Differentiation by Histone Methyltransferases and Demethylases
Epigenetic Inheritance and Reprogramming in Plants and Fission Yeast
A Novel Epigenetic Mechanism in Drosophila Somatic Cells Mediated by PIWI and piRNAs
Small RNA Silencing Pathways in Germ and Stem Cells
Adult Stem Cells
Epithelial Stem/Progenitor Cells in Lung Postnatal Growth, Maintenance, and Repair
Multipotent Islet-1 Cardiovascular Progenitors in Development and Disease
Regulation of Skeletal Muscle Stem Cell Behavior by Pax3 and Pax7
Regulation and Function of Skeletal Muscle Stem Cells
The Molecular Regulation of Muscle Stem Cell Function
Building Epithelial Tissues from Skin Stem Cells
Very Long-term Self-renewal of Small intestine, Colon, and Hair Follicles from Cycling Lgr5+ve Stem Cells
Neural Stem Cells and Brain Tumors
The Heterogeneity of Adult Neural Stem Cells and the Emerging Complexity of Their Niche
Notch, Neural Stem Cells, and Brain Tumors
Human ESC-derived Neural Rosettes and Neural Stem Cell Progression
Metabolomics of Neural Progenitor Cells: A Novel Approach to Biomarker Discovery
Signaling Pathways Controlling Neural Stem Cells Slow Progressive Brain Disease
Cancer Stem Cells in Brain Tumor Biology
Neural and Cancer Stem Cells in Tumor Suppressor Mouse Models of Malignant Astrocytoma
Pten and p53 Converge on c-Myc to Control Differentiation, Self-renewal, and Transformation of Normal and Neoplastic Stem Cells in Glioblastoma
Stem Cells and Cancer
Establishment of a Normal Hematopoietic and Leukemia Stem Cell Hierarchy
Role of "Cancer Stem Cells" and Cell Survival in Tumor Development and Maintenance
The 1NK4-ARF (CDKN2A/B) Locus in Hematopoiesis and BCR-ABL induced Leukemias
Delineating the Epithelial Hierarchy in the Mouse Mammary Gland
Stem Cell Biology in the Lung and Lung Cancers: Using Pulmonary Context and Classic Approaches
Epithelial Stem Cells of the Prostate and Their Role in Cancer Progression
Role of β-catenin in Epidermal Stem Cell Expansion, Lineage Selection, and Cancer
Implications of Cellular Senescence in Tissue Damage Response, Tumor Suppression, and Stem Cell Biology
Renewal and Regeneration
Regulation of Self-renewal and Differentiation in the Drosophila Nervous System
Progenitor Cells for the Prostate Epithelium: Roles in Development, Regeneration, and Cancer
Stem Cells Use Distinct Self-renewal Programs at Different Ages
Complementary and Independent Function for Hoxb4 and Bmil in HSC Activity
Regeneration, Stem Cells, and the Evolution of Tumor Suppression
Germ Cell Specification and Regeneration in Planarians
Novel Insights into the Flexibility of Cell and Positional Identity during Urodele Limb Regeneration
Summary: Present and Future Challenges for Stem Cell Research
Author Index
Subject Index