RNA biology : an introduction / Gunter Meister. — Weinheim : Wiley-VCH, c2011. – (58.174251/M515) |
Contents
Contents
Preface XV
Part One mRNA Biology 1
1 Introduction 3
2 Transcription of Pre-mRNAs 17
3 Capping of the Pre-mRNA S' End 37
4 3' End Processing of Pre-mRNAs 45
5 Splicing of Eukaryotic Pre-mRNAs 59
6 mRNA Export from the Nucleus to the Cytoplasm 73
7 Translation 83
8 Deadenylation of mRNA 107
9 mRNA Decapping 113
10 mRNA Decay Pathways 121
11 mRNA Quality Control 137
Part Two Non-Coding RNA Biology 151
12 Ribosomal RNAs and the Biogenesis of Ribosomes 153
13 Transfer RNAs 183
14 The 7SL RNA and the Signal Recognition Particle 199
15 Regulation of Transcription: the 7SK Small Nuclear RNA 209
16 Small Nucleolar RNAs 217
17 Spliceosomal Small Nuclear RNAs 229
18 Small Non-Coding RNAs and the Mechanism of Gene Silencing 245
19 Long Non-Coding RNAs 271
20 RNA Editing 281
21 Ribozymes- Catalytic RNA Molecules 293
22 Riboswitches and RNA Sensors 303
23 RNomics 309
Appendix: Answers to Questions 319
Index 355