The chemical biology of nucleic acids / edited by Gunter Mayer. — Oxford : Wiley, 2010. – (58.174256/C517) |
Contents
Contents
1 Chemical Synthesis of Modified RNA
2 Expansion of the Genetic Alphabet in Nucleic Acids by Creating New Base Pairs
3 Chemical Biology of DNA Replication: Probing DNA Polymerase Selectivity Mechanisms with Modified Nucleotides
4 Nucleic Acid-templated Chemistry
5 Chemical Biology of Peptide Nucleic Acids (PNAs)
6 The Interactions of Small Molecules with DNA and RNA
7 The Architectural Motifs of Folded RNAs
8 Genesis and Biological Applications of Locked Nucleic Acids (LNAs)
9 Small Non-coding RNA in Bacteria
10 MicroRNA-guided Gene Silencing
11 Nucleic Acid-based Therapies
12 Innate Immune Recognition of Nucleic Acids
13 Light-responsive Nucleic Acids for the Spatiotemporal Control of Biological Processes
14 DNA Methylation
15 Frameworks for Programming RNA Devices
16 RNA as a Catalyst: The Diels-Alderase Ribozyme
17 Evolving an Understanding of RNA Function by In Vitro Approaches
18 The Chemical Biology of Aptamers: Synthesis and Applications
19 Nucleic Acids as Detection Tools
20 Bacterial Riboswitch Discovery and Analysis
Index