 |
Multi-drug resistance in cancer / edited by Jun Zhou. — [Totowa, N.J.] : Humana, c2010. – (58.17/M592/v.596) |
Contents
Contents
Contributors
1 Multidrug Resistance in Cancer
2 Multidrug Resistance in Oncology and Beyond: From Imaging of Drug Efflux Pumps to Cellular Drug Targets
3 Studying Drug Resistance Using Genetically Engineered Mouse Models for Breast Cancer
4 Mechanisms of Multidrug Resistance in Cancer
5 Molecular Mechanisms of Drug Resistance in Single-Step and Multi-Step Drug-Selected Cancer Cells
6 Pharmacogenetics of ATP-Binding Cassette Transporters and Clinical Implications
7 Flow Cytometric Evaluation of Multidrug Resistance Proteins
8 Targeted Chemotherapy in Drug-Resistant Tumors， Noninvasive Imaging of P-Glycoprotein-Mediated Functional Transport in Cancer， and Emerging Role of Pgp in Neurodegenerative Diseases 141
9 Epigenetic Regulation of Multidrug Resistance 1 Gene Expression: Profiling CpG Methylation Status Using Bisulphite Sequencing 183
10 Expression and Function of P-Glycoprotein in Normal Tissues: Effect on Pharmacokinetics 199
11 Molecular Mechanism of ATP-Dependent Solute Transport by Multidrug Resistance-Associated Protein 1
12 Impact of Breast Cancer Resistance Protein on Cancer Treatment Outcomes 251
13 Drug Ratio-Dependent Antagonism: A New Category of Multidrug Resistance and Strategies for Its Circumvention 291
14 Reversing Agents for ATP-Binding Cassette Drug Transporters 325
15 Overcoming Multidrug Resistance in Cancer: Clinical Studies of P-Glycoprotein Inhibitors
16 Pharmacokinetic and Pharmacodynamic Implications of P-Glycoprotein Modulation
17 Examination of CYP3A and P-Glycoprotein-Mediated Drug-Drug Interactions Using Animal Models 385
18 Generating Inhibitors of P-Glycoprotein: Where to， Now? 405
19 Immunosuppressors as Multidrug Resistance Reversal Agents 433
20 Overcoming Multidrug Resistance by RNA Interference 447
21 Circumventing Tumor Resistance to Chemotherapy by Nanotechnology 467
Index
