The urinary proteome : methods and protocols / edited by Alex J. Rai. — [Totowa, N.J.] : Humana Press, c2010. – (58.17/M592/v.641)

Contents

    Contents
    
    Preface
    Contributors
    1 Introduction to Urinalysis: Historical Perspectives and Clinical Application
    2 A Primer on Clinical Applications and Assays Using Urine: Focus on Analysis of Plasma Cell Dyscrasias Using Automated Electrophoresis and Immunofixation
    3 Application of Free Flow Electrophoresis to the Analysis of the Urine Proteome
    4 Standardized Preprocessing of Urine for Proteome Analysis
    5 Different Sample Preparation and Detection Methods for Normal and Lung Cancer Urinary Proteome Analysis
    6 Isolation and Purification of Exosomes in Urine
    7 Bioinformatics of the Urinary Proteome
    8 PROTIS: Use of Combined Biomarkers for Providing Diagnostic Information on Disease States
    9 Statistical Contributions to Proteomic Research 143
    10 A Review of Experimental Design Best Practices for Proteomics Based Biomarker Discovery: Focus on SELDI-TOF
    11 Urine Proteomic Profiling for Biomarkers of Acute Renal Transplant Rejection
    12 Surface Plasmon Resonance Biosensorics in Urine Proteomics 193
    13 Urinary Proteins for the Diagnosis of Obstructive Sleep Apnea Syndrome 223
    14 Immune Response Biomarker Profiling Application on ProtoArray Protein Microarrays 243
    15 Design and Validation of an Immunoaffinity LC-MS/MS Assay for the Quantification of a Collagen Type II Neoepitope Peptide in Human Urine: Application as a Biomarker of Osteoarthritis 253
    16 Cell-Specific Biomarkers in Renal Medicine and Research 271
    17 Proteomic Assays for the Detection of Urothelial Cancer 303
    18 Urine Proteomic Analysis: Use of Two-Dimensional Gel Electrophoresis， Isotope Coded Affinity Tags， and Capillary Electrophoresis
    19 Proteomic Analysis of Pancreatic Secretory Trypsin Inhibitor/Tumor-Associated Trypsin Inhibitor from Urine of Patients with Pancreatitis or Prostate Cancer
    Index