Lipidomics. v. 1, methods and protocols / edited by Donald Armstrong. — New York : Humana Press, 2009. – (58.17/M592/v.579) |
Contents
Contents
Preface
Contributors
PART I SHOTGUN AND GLOBAL LIPIDOMICS
1 Examination of the Brain Mitochondrial Lipidome Using Shotgun Lipidomics
2 Tracking the Glycerophospholipid Distribution of Docosahexaenoic Acid by Shotgun Lipidomics
3 Global Analysis of Retina Lipids by Complementary Precursor Ion and Neutral Loss Mode Tandem Mass Spectrometry 33
4 Combining Lipidomics and Proteomics of Human Cerebrospinal Fluids
PART II ANALYTICAL APPROACHES
5 Lipid Profiling Using Two-Dimensional Heteronuclear Single Quantum Coherence NMR
6 Capabilities and Drawbacks of Phospholipid Analysis by MALDI-TOF Mass Spectrometry
7 Lipidomics of the Red Cell in Diagnosis of Human Disorders
8 HPLC/MS/MS-Based Approaches for Detection and Quantification of Eicosanoids 161
9 Brain Phosphoinositide Extraction, Fractionation, and Analysis by MALDI-TOF MS 189
10 Lipidomic Analysis of Biological Samples by Liquid Chromatography Coupled to Mass Spectrometry 201
11 Lipidomic Analysis of Human Meibum Using HPLC-MS
12 Lipid Geographical Analysis of the Primate Macula by Imaging Mass Spectrometry
13 A Novel Role for Nutrition in the Alteration of Functional Microdomains on the Cell Surface 261
14 Lipidomic Analysis of Prostanoids by Liquid Chromatography-Electrospray Tandem Mass Spectrometry 271
15 Qualitative and Quantitative Analyses of Phospholipids by LC-MS for Lipidomics 287
16 Determination of Fatty Acid Profiles and TAGs in Vegetable Oils by MALDI-TOF/MS Fingerprinting 315
17 Dynamics of Adipose Tissue Development by2H2O Labeling
18 Analysis of Lipid Particles from Yeast
19 Mammalian Fatty Acid Elongases 375
20 Membrane Lipidomics and the Geometry of Unsaturated Fatty Acids: From Biomimetic Models to Biological Consequences 391
21 OnLine Ozonolysis Methods for the Determination of Double Bond Position in Unsaturated Lipids 413
22 Comprehensive Quantitative Analysis of Bioactive Sphingolipids High-Performance Liquid Chromatography-Tandem Mass Spectrometry 443
23 The Use of Charged Aerosol Detection with HPLC for the Measurement of Lipids 469
PART III LIPID MAPS
24 Non-invasive Mapping of Lipids in Plant Tissue Using Magnetic Resonance Imaging
25 Mapping the Lipolytic Proteome of Adipose Tissue Using Fluorescent Suicide Inhibitors 497
26 Identifying the Spatial Distribution of Vitamin E, Pulmonary Surfactant and Membrane Lipids in Cells and Tissue by Confocal Raman Microscopy
Index