International review of cell and molecular biology. v. 277 / edited by Kwang W. Jeon. — Amsterdam : Elsevier, c2009. – (58.15/I61/v.277)

Contents

    CONTENTS
    
    Contributors
    1. Focal Adhesions: New Angles on an Old Structure
    1. Introduction
    2. Formation of ECM Adhesions
    3. Role of Syndecan-4 in Focal Adhesion Formation
    4. Focal Adhesions on Biomaterial Surfaces
    5. Mechanotransduction
    6. Disassembly of Focal Adhesions
    7. Concluding Remarks
    Acknowledgments
    References
    2. Calcineurin Signaling and the Slow Oxidative Skeletal Muscle Fiber Type
    1. Introduction
    2. Importance of Oxidative Skeletal Muscle Fiber Phenotype
    3. Calcium-Dependent Mediators of Oxidative Muscle Fiber Type Programing
    4. Biological Functions of the Calcineurin Signaling Pathway
    5. Downstream Effector Targets of Calcineurin in Skeletal Muscle
    6. Exploiting the Beneficial Effects of Calcineurin Signaling in Skeletal Muscle
    7. Concluding Remarks
    Acknowledgment
    References
    3. New Insights into Plant Vacuolar Structure and Dynamics 103
    1. Introduction
    2. Methods to Reveal Vacuolar Structure and Dynamics
    3. Vacuolar Structure and Functions
    4. Regulation of Vacuolar Structure and Dynamics
    5. Concluding Remarks
    References
    4. Cytomechanics of Hair: Basics of the Mechanical Stability
    1. Introduction
    2. Morphology of the Hair Fiber
    3. Chemical Composition of Human Hair
    4. Interactions of Keratin Proteins
    5. Mechanical Models
    6. Concluding Remarks
    References
    5. Nuclear Actin-Related Proteins in Epigenetic Control
    1. Introduction
    2. Nuclear ARPs as Epigenetic Factors
    3. Evolutionary Origin and Phylogeny of Nuclear ARPs
    4. Function of the Nuclear ARPs in Chromatin Remodeling and Modifying Complexes
    5. Isoforms of ARP Complexes
    6. Role of Nuclear ARPs in the Epigenetic Control of Morphological Development
    7. Nuclear ARPs and Epigenetics in Human Disease
    8. Conclusions
    Acknowledgments
    References
    6. Application of New Methods for Detection of DNA Damage and Repair
    1. Introduction
    2. Indirect Detection of Double-Strand DNA Breaks and Homology-Dependent Repair
    3. Methods Based on Changes of Physical Properties of Proteins Involved in Nucleotide Excision and Postreplication Repair
    4. New Methods for Analyzing UV-Induced DNA Repair Synthesis and Chromatin Modifications
    5. Direct Detection of Damaged Nucleotides Using Specific Antibodies and Other Methods
    6. Conclusions and Perspectives
    Acknowledgments
    References
    Index
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