Cellular respiration and carcinogenesis / Shireesh P. Apte, Rangaprasad Sarangarajan, editors ; foreword by George L. Semenza, editors. — New York, N.Y. : Springer, c2009. – (64.84/C393)

Contents

    Contents
    
    Oxidative Phosphorylation and Cancer: The Ongoing Warburg Hypothesis
    The Electron Transport Chain and Carcinogenesis 19
    Respiratory Control of Redox Signaling and Cancer
    Cellular Respiration and Dedifferentiation
    Cellular Adaptations to Oxidative Phosphorylation Defects in Cancer 55
    Regulation of Glucose and Energy Metabolism in Cancer Cells by Hypoxia Inducible Factor 1 73
    The Role of Glycolysis in Cellular Immortalization 91
    Metabolic Modulation of Carcinogenesis
    Mitochondrial DNA Mutations in Tumors
    Cellular Respiration and Tumor Suppressor Genes 131
    Uncoupling Cellular Respiration: A Link to Cancer Cell Metabolism and Immune Privilege 145
    How Cancer Cells Escape Death
    Index 179