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Essentials of stem cell biology / editors, Robert Lanza [et al.]. — 2nd ed. — San Diego, Calif. ; London : Academic, 2009. – (58.155/E78/2nd ed.) |
Contents
Contents
Part I Introduction to Stem Cells
1. Pluripotential Stem Cells from Vertebrate Embryos: Present Perspective and Future Challenges
2. Embryonic Stem Cells in Perspective
3. The Development of Epithelial Stem Cell Concepts
4. Direct Reprogramming of Somatic Cells to a Pluripotent State
5. Clinical Translation of Stem Cells
Part II Basic Biology/Mechanisms
6. Molecular Bases of Pluripotency
7. Stem Cell Niches 61
8. Mechanisms of Stem Cell Self-renewal
9. Cell Cycle Regulators in Adult Stem Cells 81
10. Epigenetic Mechanisms of Cellular Memory During Development 89
11. Cell Fusion and the Differentiated State 105
12. How Cells Change Their Phenotype
Part III Tissue and Organ Development 117
13. Differentiation in Early Development 119
14. Primordial Germ Cells in Mouse and Human 131
15. Stem Cells in Extraembryonic Lineages
16. Amniotic Fluid-Derived Pluripotential Cells
17. Cord Blood Hematopoietic Stem and Progenitor Cells
18. Neurogenesis in the Vertebrate Embryo 157
19. The Nervous System
20. Neuronal Progenitors in the Adult Brain: From Development to Regulation
21. Sensory Epithelium of the Eye and Ear: Update of Retinal Stem Cell Research 2003 to the Present 185
22. Epithelial Hair Follicle Stem Cells 189
23. The Ontogeny of the Hematopoietic System 199
24. Hematopoietic Stem Cells 211
25. Red Blood Cells 217
26. Cell Differentiation in the Skeleton 223
27. Human Vascular Progenitor Cells 227
28. MultipotentAdult Progenitor Cells 233
29. Mesenchymal Stem Cells
30. Skeletal Muscle Stem Cells 249
31. Stem Cells and the Regenerating Heart 259
32. Potential of Embryonic and Induced Pluripotent Stem Cell Differentiation Culture for Vascular Biology 265
33. Cell Lineages and Stem Cells in the Embryonic Kidney 273
34. Adult Liver Stem Cells
35. Pancreatic Stem Cells 299
36. Stem Cells in the Gastrointestinal Tract 307
Part IV Methods 329
37. Induced Pluripotent Stem Cell Derivation 331
38. Characteristics and Characterization of Human Pluripotent stem cells
39. Isolation and maintenance of Murine embryonic stem cells
40. Isolation， characterization and maintenance of primate embryonic stem cells
41. Approaches for Derivation and Maintenance of Human Embryonic Stem Cells: Detailed Procedures and Alternatives 365
42. Derivation and Differentiation of Human Embryonic Germ Cells 381
43. Growth Factors and the Serum-free Culture of Human Pluripotent Stem Cells
44. Feeder-free Culture 397
45. Genetic Manipulation of Human Embryonic Stem Cells 409
46. Homologous Recombination in Human Embryonic Stem Cells 417
47. Surface Antigen Markers
48. Lineage Marking
49. Genomic Reprogramming
50. Isolation and Characterization of Hematopoietic Stem Cells 443
51. Microarray Analysis of Stem Cells and Differentiation 449
52. Zebrafish and Stem Cell Research 459
Part V Applications
53. Cancer Stem Cells
54. Neural Stem Cells for Central Nervous System Repair 485
55. Spinal Cord Injury 497
56. Use of Embryonic Stem Cells to Treat Heart Disease 507
57. Insulin-producing Cells Derived from Stem Cells: A Potential Treatment for Diabetes 513
58. Burns and Skin Ulcers 523
59. Stem Cells and Heart Disease 529
60. Stem Cells for the Treatment of Muscular Dystropy: Therapeutic Perspectives 543
61. Regeneration of Epidermis from Adult Keratinocyte Stem Cells
62. Orthopedic Applications of Stem Cells 437
63. Embryonic Stem Cells in Tissue Engineering 571
64. Postnatal Stem Cells in Tissue Engineering 583
65. Stem Cell Gene Therapy 591
Part VI Regulation and Ethics
66. Ethical Considerations
67. Stem Cell Research: Religious Considerations
68. Stem Cell-based Therapies: Food and Drug Administration Product and Pre-Clinical Regulatory Considerations 619
69. It's Not About Curiosity， It's About Cures: People Help Drive Progress 631
