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International review of cell and molecular biology. v. 275 / edited by Kwang W. Jeon. — Amsterdam : Elsevier, c2009. – (58.15/I61/v.275)

Contents

    CONTENTS
    
    Contributors
    1. Ceil and Molecular Biology of Invadopodia
     1. Introduction
     2. Biogenesis, Molecular Components, and Activity
     3. Open Questions and Concluding Remarks
     References
    2. Viral Channel-Forming Proteins
     1. Introduction
     2. Channel-Forming Proteins
     3. Detecting a Channel-Forming Protein
     4. Functional and Structural Characterization
     5. Channel-Forming Proteins in Antiviral Therapy
     6. Concluding Remarks
     References
    3. Notch Signaling in Chondrogenesis
     1. Introduction
     2. Helix-Loop-Helix Proteins
     3. Notch Genes
     4. Notch1 as a Marker for Progenitor Cells in Adult Cartilage
     5. Function of Notch Signaling During Chondrogenesis
     6. Notch Signaling in Osteoarthritis
     7. Concluding Remarks
     References
    4. The Controversial Role of Mast Cells in Tumor Growth
     1. Introduction
     2. Biological Functions of Mast Cells
     3. Mast Cell Development, Anatomical Distribution, and Phenotype
     4. Mast Cell-Derived Secretory Products
     5. Mast Cells in Experimental Carcinogenesis
     6. Mast Cells and Tumor Growth in Humans: Pro and Contra
     7. Mast Cells and Tumor Angiogenesis and Lymphangiogenesis
     8. Concluding Remarks
     References
    5. Limbal Stem Cells: Application in Ocular Biomedicine
     1. Introduction
     2. Ocular Surface and Limbal Stem Cells
     3. Conventional Treatment Modalities of Limbal Stem Cell Deficiency
     4. Concept of Cultivated Limbal Stem Cell Transplantation
     5. Review of Literature on Clinical Trials
     6. Concluding Remarks
     References
    6. Cell and Molecular Biology of the Novel Protein Tyrosine-Phosphatase-Interacting Protein 51
     1. Introduction
     2. Molecular Biology of PTPIP51
     3. Signaling Partners of PTPIP51
     4. Expression Profile of PTPIP51
     5. Conclusions and Further Perspective
     References
    Index