Inflammation and cancer : methods and protocols. v. 2, Molecular analysis and pathways / edited by Serguei V. Kozlov. — Totowa, N.J. : Humana Press ; [London : Springer, distributor], c2009. – (58.17/M592/v.512) |
Contents
Contents
Preface
Contents of Volume I
Contributors
PART I: CROSSROADS OF INFLAMMATION AND CANCER: MOLECULAR ASPECTS
1 Immunohistochemical Analysis of 8-Nitroguanine, A Nitrative DNA Lesion, in Relation to Inflammation-Associated Carcinogenesis
2 Molecular Analysis of Genetic Instability Caused by Chronic Inflammation
3 Obesity Provides a Permissive Milieu in Inflammation-Associated Carcinogenesis: Analysis of Insulin and IGF Pathways
4 Detecting and Modulating the NF-κB Activity in Human Immune Cells Generation of Human Cell Lines with altered Levels of NF-κB
5 Inflammation-Related Aberrant Patterns of DNA Methylation: Detection and Role in Epigenetic Deregulation of Cancer Cell Transcriptome
6 cDNA Microarray Analysis of Inflammatory Breast Cancer Signatures
7 Analysis of the TLR/NF-κB Pathway in Antigen-Presenting Cells in Malignancies Promoted by Inflammation
8 Induced Nitric Oxide Synthase as a Major Player in the Oncogenic Transformation of Inflamed Tissue
PART II: MOLECULAR AND CELLULAR APPROACHES TO DIAGNOSTICS AND DRUG TARGET DISCOVERY IN INFLAMMATION-RELATED ONCOGENESIS
9 Development of a Cell-Based Assay to Quantify the Inflammatory Potential of Test Substances and Screen Compound Libraries for Anti-cancer Drug Candidates in a High-Throughput Format
10 The NF-κB Transcription Factor Pathway as a Therapeutic Target in Cancer: Methods for Detection of NF-κB Activity 169
11 Inhibiting Proinflammatory NF-κB Signaling Using Cell-Penetrating NEMO Binding Domain Peptides
12 Quantitative Measurement of Cytokine Expression in Synoviocytes Derived from Rheumatoid Arthritis Patients
13 Molecular Characterization of Infammation-Induced JNK/c-Jun Signaling Pathway in Connection with Tumorigenesis
14 Molecular Characterization of STAT Signaling in Inflammation and Tumorigenesis
15 Inflammation and Tumor Progression: A Lesson from TNF-α-Dependent FAK Signaling in Cholangiocarcinoma
16 Cyclooxygenase Inhibitors Induce Colon Cancer Cell Apoptosis Via PPARδ-- 14-3-38 Pathway
17 PPARβ/δ Agonist Increases the Expression of PGE2 Receptor Subtype EP4 in Human Lung Carcinoma Cells
18 Investigating Macrophage and Malignant Cell Interactions In Vitro
19 Cellular Magnetic Resonance Imaging Using Superparamagnetic Anionic Iron Oxide Nanoparticles: Applications to In Vivo Trafficking of Lymphocytes and Cell-Based Anticancer Therapy
20 Application of Phage Display to Discovery of Tumor-Specific Homing Peptides: Developing Strategies for Therapy and Molecular Imaging of Cancer
21 Molecular Basis of Histone Deacetylase Inhibitors as New Drugs for the Treatment of Inflammatory Diseases and Cancer
22 Peptide YY Mediates Inhibition of Tumor Growth and Inflammation