Bioinformatics and functional genomics / by Jonathan Pevsner. — 2nd ed. — Hoboken, N.J. : Wiley-Blackwell, c2009. – (58.1423/P514/2nd ed.)

Contents

    Contents
    
    PART l ANALYZING INA， BNA， ANI PBOTEIN SEQUENCES IN IATABASES
    1 Introduction， 3
    2 Access to Sequence Data and Literature Information， 13
    3 Pairwise Sequence Alignment， 47
    4 Basic Local Alignment Search Tool (BLAST)， 101
    5 Advanced Database Searching， 141
    6 Multiple Sequence Alignment， 179
    7 Molecular Phylogeny and Evolution， 215
    PART II GENOMEWIDE ANALYSIS OF BNA AND PROTEIN
    8 Bioinformatic Approaches to Ribonucleic Acid (RNA)， 279
    9 Gene Expression: Microarray Data Analysis， 331
    10 Protein Analysis and Proteomics， 379
    11 Protein Structure， 421
    12 Functional Genomics， 461
    PART III GENOME ANALYSS
    13 Completed Genomes， 517
    14 Completed Genomes: Viruses， 567
    15 Completed Genomes: Bacteria and Archaea， 597
    16 The Eukaryotic Chromosome， 639
    17 Eukaryotic Genomes: Fungi， 697
    18 Eukaryotic Genomes: From Parasites to Primates， 729
    19 Human Genome， 791
    20 Human Disease， 839
    Glossary， 891
    Answers to Self-Test Quizzes， 909
    Author Index， 911
    Subject Index， 913