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新书资源(2009年7月)

Proteases and cancer : methods and protocols / edited by Toni M. Antalis and Thomas H. Bugge. — [Totowa, N.J.] : Humana, c2009. – (58.17/M592/v.539)

Contents

    Contents
    
    Preface
    Contributors
    1 Delineating Protease Functions During Cancer Development
    2 Proteolytic Systems: Constructing Degradomes 33
    3 Microarrays for Protease Detection in Tissues and Cells
    4 Positional Scanning Synthetic Combinatorial Libraries for Substrate Profiling
    5 Mixture-Based Peptide Libraries for Identifying Protease Cleavage Motifs
    6 High Throughput Substrate Phage Display for Protease Profiling
    7 Imaging Specific Cell Surface Protease Activity in Living Cells Using Keengineered Bacterial Cytotoxins
    8 Cell-Based Identification of Natural Substrates and Cleavage Sites for Extracellular Proteases by SILAC Proteomics
    9 Optical Proteolytic Beacons for In Vivo Detection of Matrix Metalloproteinase Activity
    10 Dissecting the Urokinase Activation Pathway Using Urokinase-Activated Anthrax Toxin 175
    11 On-Demand Cleavable Linkers for Radioimmunotherapy 191
    Index