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Cortical development : genes and genetic abnormalities. — Chichester : Wiley, c2007. – (59.5978/C829) |
Contents
Contents
Symposium on Cortical development: genes and genetic abnormalities， held at the Novartis Foundation， London， 6-8 February 2007
Editors: Gregory Bock (Organizer) and Jamie Goode
This symposium is based on a proposal made by Zoltan Molnar
Chair's introduction 1
Molecular development of corticospinal motor neuron circuitry
Discussion 15
Perspectives on the developmental origins of cortical interneuron diversity 21
Discussion 35
Genetic determinants of neuronal migration in the cerebral cortex 45
Discussion 53
Neural stem and progenitor cells in cortical development 59
Discussion 73
Genes that control the size of the cerebral cortex 79
Discussion 91
General discussion I 96
Control of cortical neuron layering: lessons from mouse chimeras 99
Discussion 108
Intracortieal multidirectional migration of cortical interneurons 116
Discussion 125
The atypical cadherin Celsr3 regulates the development of the axonal blueprint 130
Discussion 134
Regulation of laminar and area patterning of mammalian neocortex and behavioural implications 141
Discussion 159
Genetic regulation of prefrontal cortex development and function 165
Discussion 173
Self-organization and pattern formation in primate cortical networks 178
Discussion 195
Molecular mechanisms of thalamocortical axon targeting 199
Discussion 208
Genes involved in the formation of the earliest cortical circuits 212
Discussion 224
Emx and Nfi genes regulate cortical development and axon guidance in the telencephalon 230
Discussion 242
Schizophrenia susceptibility genes and their neurodevelopmental implications: focus on neuregulin 1 246
Discussion 255
Focal brain malformations: a spectrum of disorders along the mTOR cascade 260
Discussion 272
Final discussion 276
Index of contributors 282
Subject index 284
