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Cardiovascular regeneration and stem cell therapy / edited by Annarosa Leri, Piero Anversa, William H. Frishman. — Malden, Mass. : Blackwell, c2007. – (63.91/C267r)

Contents

        Contents
    
    Contributors, vii
    Preface, xi
    Introduction, 1
    Part I Stem cell biology, 3
    1 Homing of stem cells and tissue injury, 5
    2 Adult stem cell plasticity: lineage potential on a continuum, 11
    3 Embryonic stem cells and cardiogenesis, 25
    4 Mesenchymal stem-cell-derived cardiomyogenic cells, 37
    5 Bone marrow cells and vascular growth, 47
    6 Progenitor cells and vascular repair, 57
    Part II Cardiac progenitor cells in the adult heart, 67
    7 Cardiac side population cells: phenotype and functional significance, 69
    8 Phenotype and function of c-kit+-derived amplifying myocytes, 77
    9 Cardiac stem cells and their niches, 87
    10 Activation of the local regenerative system of the heart, 95
    Part III Progenitor cells and the diseased heart, 103
    11 Embryonic stem cells and myocardial regeneration, 105
    12 Bone-marrow-derived cells in myocardial repair and regeneration, 117
    13 Endothelial progenitor cells and the infarcted heart, 129
    14 Cytokines and heart remodeling, 139
    15 IGF-1, muscle progenitors, and heart failure, 149
    Part IV Cardiac progenitor cells and heart failure, 159
    16 Cardiac stem cells and diabetic cardiomyopathy, 161
    17 Stem cells and cardiac aging, 171
    18 Bioengineered scaffolds: myocytes, endothelial cells and cardiac repair, 183
    19 Gene therapy and cellular therapy in cardiac repair, 193
    20 Cardiac stem cells and the failing heart, 201
    21 Myocardial infarction: risks and hope, 211
    Part V Future directions, 219
    22 Conclusions- future directions, 221
    Index, 225