Cardiovascular regeneration and stem cell therapy / edited by Annarosa Leri, Piero Anversa, William H. Frishman. — Malden, Mass. : Blackwell, c2007. – (63.91/C267r) |
Contents
Contents
Contributors, vii
Preface, xi
Introduction, 1
Part I Stem cell biology, 3
1 Homing of stem cells and tissue injury, 5
2 Adult stem cell plasticity: lineage potential on a continuum, 11
3 Embryonic stem cells and cardiogenesis, 25
4 Mesenchymal stem-cell-derived cardiomyogenic cells, 37
5 Bone marrow cells and vascular growth, 47
6 Progenitor cells and vascular repair, 57
Part II Cardiac progenitor cells in the adult heart, 67
7 Cardiac side population cells: phenotype and functional significance, 69
8 Phenotype and function of c-kit+-derived amplifying myocytes, 77
9 Cardiac stem cells and their niches, 87
10 Activation of the local regenerative system of the heart, 95
Part III Progenitor cells and the diseased heart, 103
11 Embryonic stem cells and myocardial regeneration, 105
12 Bone-marrow-derived cells in myocardial repair and regeneration, 117
13 Endothelial progenitor cells and the infarcted heart, 129
14 Cytokines and heart remodeling, 139
15 IGF-1, muscle progenitors, and heart failure, 149
Part IV Cardiac progenitor cells and heart failure, 159
16 Cardiac stem cells and diabetic cardiomyopathy, 161
17 Stem cells and cardiac aging, 171
18 Bioengineered scaffolds: myocytes, endothelial cells and cardiac repair, 183
19 Gene therapy and cellular therapy in cardiac repair, 193
20 Cardiac stem cells and the failing heart, 201
21 Myocardial infarction: risks and hope, 211
Part V Future directions, 219
22 Conclusions- future directions, 221
Index, 225