Nanostructure design : methods and protocols / edited by Ehud Gazit, Ruth Nussinov. — Totowa, N.J. : Humana Press, c2008. – (58.17/M592/v.474)

Contents

    Contents
    
    Preface
    Contributors
    PART I EXPERIMENTAL APPROACH
    1 Molecular Design of Performance Proteins With Repetitive Sequences: Recombinant Flagelliform Spider Silk as Basis for Biomaterials 3
    2 Creation of Hybrid Nanorods of Natural Trimeric Fibrous From Sequences Proteins Using the Fibritin Trimerization Motif 15
    3 The Leucine Zipper as a Building Block for Self-Assembled Protein Fibers 35
    4 Biomimetic Synthesis of Bimorphic Nanostructures 53
    5 Synthesis and Primary Characterization of Self-Assembled Peptide-Based Hydrogels
    6 Periodic Assembly of Nanospecies on Repetitive DNA Sequences Generated on Gold Nanoparticles by Rolling Circle Amplification
    PART II COMPUTATIONAL APPROACH
    7 Protocols for the In Silico Design of RNA Nanostructures 93
    8 Self-Assembly of Fused Homo-OI
    9 Computational Methods in Nanostructure Design: Replica Exchange Simulations of Self-Assembling Peptides 133
    10 Modeling Amyloid Fibril Formation: A Free-Energy Approach 153
    11 Computer Modeling in Biotechnology: A Partner in Development 181
    12 What Can We Learn From Highly Connected β-Rich Structures for Structural Interface Design? 235