Genetics of sexual differentiation and sexually dimorphic behaviors / edited by Daisuke Yamamoto. — Amsterdam : Elsevier, c2007. – (58.14/A244/v.59)

Contents

    Contents
    
    Contributors
    Preface
    1. Genetic Control of Sex Differences in C. elegans Neurobiology and Behavior
    I. Introduction 2
    II. Main Text 4
    III. Conclusions 29
    2. The Neural and Genetic Substrates of Sexual Behavior in Drosophila 39
    I. Hypothesis on the Master Control Gene for Behavior
    II. Discovery of fru Mutants and Their Phenotypic Characteristics 42
    III. Molecular Biology of fru Locus 49
    IV. Cellular Basis of fru Functions in Male Courtship Behavior 53
    V. Conclusions 58
    3. Sexual Differentiation of the Vocal Control System of Birds 67
    I. Introduction 68
    II. Sex-Specific and Sex-Typical Vocalizations 70
    III. The Endocrinology of Birds' Vocalization 72
    IV. Steroid Sensitivity of the Vocal Control System of Afferent Auditory Regions and Modulatory Systems 75
    V. Sexual Dimorphisms of the Vocal Control System of Songbirds 84
    VI. Sexual Differentiation of the Vocal Control System of Songbirds 87
    VII. Sexual Differentiation of Vocal Control Areas in Adulthood 91
    4. Gene Regulation as a Modulator of Social Preference in Voles 107
    I. Introduction 108
    II. Oxytocin and Pair Bonding in Voles 110
    III. Vasopressin and Pair Bonding in Voles 111
    IV. Gene Regulation in Male Species-Typical Behavior Evolutionary Tuning Knobs
    V. Sexual Dimorphism 121
    VI. Coda 122
    5. Genetic Basis for MHC-Dependent Mate Choice 129
    I. Introduction 130
    II. The MHC 130
    III. Mouse Mating Preferences 131
    IV. Functions of MHC-Mediated Mating Preference 132
    V. Familial Imprinting Determines H-2 Selective Mating Preferences 133
    VI. Pregnancy Block 134
    VII. Parent-Infant Recognition 135
    VIII. Chemosensory Discrimination 136
    IX. MHC-Dependent Mating Preferences in Other Taxa 137
    X. HLA: Odortypes and Mate Selection in Humans 138
    XI. Conclusions and Implications for Future Work 139
    6. Molecular Biology of Peptide Pheromone Production and Reception in Mice 147
    I. Introduction 148
    II. Intraspecies Effects of Volatile Pheromones in Mice 150
    III. Peptides and Proteins as Social Signals in Mice 151
    IV. The Exocrine Gland-Secreting Peptide Family in Mice 152
    V. Molecular Biology of Pheromone Reception 157
    VI. Pheromone Signals to the Brain 162
    VII. Pheromones and Evolution 163
    VIII. Concluding Remarks 165
    7. Environmental Programming of Phenotypic Diversity in Female Reproductive Strategies 173
    I. Introduction 174
    II. Main Text 178
    III. Conclusion 204
    8. Genomic Imprinting and the Evolution of Sex Differences in Mammalian Reproductive Strategies 217
    I. Introduction 218
    II. Placental Regulation of Maternal Endocrine Function and Behavior 220
    III. Genomic Imprinting: Coadaptive Evolution of Brain and Placenta 222
    IV. Genomic Imprinting， Hypothalamic Development， and Behavior 226
    V. Sex Differences in the Rodent VNO Pathway 228
    VI. Brain Evolution and Behavior: A Role for Genomic Imprinting 231
    VII. Conclusions 237
    9. Sex Differences in Brain and Behavior: Hormones Versus Genes 245
    1. Role of SRY in Sex Determination 246
    II. Male and Female Brains are Different 247
    III. The Central DOGMA of Sexual Differentiation 247
    IV. Sex Hormones in Brain Sexual Differentiation 248
    V. Exceptions to the DOGMA 248
    VI. Evidence for a Direct Role of SRY in the Brain 250
    VII. Sexual Orientation is a Sexually Dimorphic Trait 251
    VIII. Homosexual Brains are Different 253
    IX. The Role of Prenatal Androgen Exposure on Sexual Orientation: Myth or Reality?
    X. Indirect Hormonal Measures 255
    XI. The Genetics of Sexual Orientation 256