Long-range control of gene expression / edited by Veronica van Heyningen, Robert E. Hill. — Amsterdam : Elsevier, c2008. – (58.14/A244/v.61)

Contents

    Contents
    
    Contributors xi
    Preface xiii
    1. Chromatin Structure and the Regulation of Gene Expression: the lessons of PEV in drosophila
    2. Polycomb Group Proteins and Long-Range Gene Regulation 45
    3. Evolution of Cis-Regulatory Sequences in Drosophila
    4. β-Globin Regulation and Long-Range Interactions 107
    5. Long-Range Regulation of α-Globin Gene Expression 143
    6. Global Control Regions and Regulatory Landscapes in Vertebrate Development and Evolution 175
    7. Regulation of Imprinting in Clusters: Noncoding RNAs Versus Insulators 207
    8. Genomic Imprinting and Imprinting Defects in Humans 225
    9. Epigenetic Gene Regulation in Cancer
    10. Genomic Identification of Regulatory Elements by evolutionary sequence comparison and functional analysis
    11. Regulatory Variation and Evolution: Implications for Disease 295
    12. Organization of Conserved Elements Near Key Developmental Regulators in Vertebrate Genomes 307
    13. Long-Range Gene Control and Genetic Disease 339