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新书资源(2008年10月)

Biological thermodynamics / Donald T. Haynie. — 2nd ed. — Cambridge ; New York : Cambridge University Press, 2008. – (58.1714/H424/2nd ed.)

Contents

            Contents
    
    Preface to the second edition
    Chapter I Energy transformation
    A. Introduction
    B. Distribution of energy
    C. System and surroundings
    D. Animal energy consumption
    E. Carbon, energy, and life
    F. References and further reading
    G. Exercises
    Chapter 2 The First Law of Thermodynamics
    A. Introduction
    B. Internal energy
    C. Work
    D. The First Law in operation
    E. Enthalpy
    F. Standard state
    G. Some examples from biochemistry
    H. Heat capacity
    I. Energy conservation in the living organism
    J. References and further reading
    K. Exercises
    Chapter 3 The Second Law of Thermodynamics
    A. Introduction
    B. Entropy
    C. Heat engines
    D. Entropy of the universe
    E. Isothermal systems
    F. Protein denaturation
    G. The Third Law and biology
    H. Irreversibility and life
    I. References and further reading
    J. Exercises
    Chapter 4 I Gibbs free energy – theory
    A. Introduction
    B. Equilibrium
    C. Reversible processes
    D. Phase transitions
    E. Chemical potential
    F. Effect of solutes on boiling points and freezing points
    G. Ionic solutions
    H. Equilibrium constant
    I. Standard state in biochemistry
    J. Effect of temperature on Keq
    K. Acids and bases
    L. Chemical coupling
    M. Redox reactions
    N. References and further reading
    O. Exercises
    Chapter 5 Gibbs free energy - applications
    A. Introduction
    B. Photosynthesis, glycolysis, and the citric acid cycle
    C. Oxidative phosphorytation and ATP hydrolysis
    D. Substrate cycling
    E. Osmosis
    F. Dialysis
    G. Donnan equilibrium
    H. Membrane transport
    I. Enzyme-substrate interaction
    J. Molecular pharmacology
    K. Hemoglobin
    L. Enzyme-linked immunosorbent assay (ELISA)
    M. DNA
    N. Polymerase chain reaction (PCR)
    O. Free energy of transfer of amino acids
    P. Protein solubility
    Q. Protein stability
    R. Protein dynamics
    S. Non-equilibrium thermodynamics and life
    T. References and further reading
    U. Exercises
    Chapter 6 Statistical thermodynamics
    A. Introduction
    B. Diffusion
    C. Boltzmann distribution
    D. Partition function
    E. Analysis of thermodynamic data
    F. Multi-state equilibria
    G. Protein heat capacity functions
    H. Cooperative transitions
    I. "Interaction" free energy
    j. elix-coil transition theory
    K. References and further reading
    L. Exercises
    Chapter 7 Binding equilibria
    A. Introduction
    B. Single-site model
    C. Multiple independent sites
    D. Oxygen transport
    E. Scatchard plots and Hill plots
    F. Allosteric regulation
    G. Proton binding
    H. References and further reading
    I. Exercises
    Chapter 8 Reaction kinetics
    A. Introduction
    B. Rate of reaction
    C. Rate constant and order of reaction
    D. First-order and second-order reactions
    E. Temperature effects
    F. Collision theory
    G. Transition state theory
    H. Electron transfer kinetics
    I. Enzyme kinetics
    J. Inhibition
    K. Reaction mechanism of lysozyme
    L. Hydrogen exchange
    M. Protein folding and pathological misfolding
    N. Polymerization
    O. Muscle contraction and molecular motors
    P. References and further reading
    Q. Exercises
    Chapter 9 The frontier of biological thermodynamics
    A. Introduction
    B. What is energy?
    C. The laws of thermodynamics and our universe
    D. Thermodynamics of (very) small systems
    E. Formation of the first biological macromolecules
    F. Bacteria
    G. Energy, information, and life
    H. Biology and complexity
    I. The Second Law and evolution
    J. References and further reading
    K. Exercises
    Appendices
    A. General references
    B. Biocalorimetry
    C. Useful tables
    D. BASIC program for computing the intrinsic rate of amide hydrogen exchange from the backbone of a polypeptide
    Glossary
    Index of names
    Subject index