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The aminoacyl-tRNA synthetases / [edited by] Michael Ibba, Christopher Francklyn, Stephen Cusack. — Georgetown, Tex., U.S.A. : Landes Bioscience : Eurekah.com, c2005. – (58.174251/A517) |
Contents
CONTENTS
Preface xiv
1. The World of Aminoacyl-tRNA Synthetases 1
2. Arginyl-tRNA Synthetases 3
3. Cysteinyl-tRNA Synthetases 12
4. Isoleucyl-tRNA Synthetases 24
5. Leucyl-tRNA Synthetases 36
6. Methionyl-tRNA Synthetases 47
7. Valyl-tRNA Synthetases 59
8. Class I Lysyl-tRNA Synthetases 68
9. Glutaminyl-tRNA Synthetases 73
10. Glutamyl-tRNA Synthetases 89
11. Trytophanyl-tRNA Synthetases 99
12. Tyrosyl-tRNA Synthetases 111
13. Glycyl-tRNA Synthetases 125
14. Histidyl-tRNA Synthetases 135
15. Prolyl-tRNA Synthetases 149
16. Threonyl-tRNA Synthetases 162
17. Seryl-tRNA Synthetases 177
18. Asparaginyl-tRNA Synthetases 193
19. Aspartyl-tRNA Synthetases 210
20. Class II Lysyl-tRNA Synthetases 227
21. Alanyl-tRNA Synthetases 241
22. Phenylalanyl-tRNA Synthetases ;.. 250
23. tRNA Aminoacylation: The Crucial Roles of tRNA Deformability and Backbone-Mediated Interactions by Synthetase 266
24. Mitochondrial Aminoacyl-tRNA Synthetases 271
25. tRNA Synthetase-Like Proteins 285
26. Multi-Aminoacyl-tRNA Synthetase Complexes 298
27. Regulation of Aminoacyl-tRNA Synthetase Gene Expression in Bacteria 309
28. Transfer RNA-Dependent Amidotransferases: Key Enzymes for Asn-tRNA and Gln-tRNA Synthesis in Nature 314
29. Selenocysteine 320
30. Catalysis of the tRNA Aminoacylation Reaction 328
31. Proteins with One or More Unnatural Amino Acids 353
32. Ribozyme-Catalyzed tRNA Aminoacylation 364
33. Protein Tagging and Ribosome Rescue in Bacteria Requires the Recognition of Transfer-Messenger RNA by an Aminoacyl-tRNA Synthetase 375
34. Accuracy of Aminoacyl-tRNA Synthetases: Proofreading of Amino Acids 384
35. Aminoacyl-tRNA Synthetases and Disease 397
36. Aminoacyl-tRNA Synthetases As Anti-Infective Drug Targets 405
