Encyclopedia of toxicology = 毒理学百科. 精选卷 / editor-in-chief, Philip Wexler ; associate editors, Bruce D. Anderson ... [et al.]. — 2nd ed.,[reprinted ed.]. — Beijing : Science Press ; Oxford, UK : Elsevier, c2007. – (63.33072/E56(R))

Contents

    目 录<br>    
    Aberrations of Chromosomes(染色体畸变，染色体异常) 1
    Absorption(吸收) 1
    Acceptable Daily Intake(ADI)(每日允许摄入量) 6
    Aggregate Exposures(累积照射) 8
    Ames Test(埃姆斯试验)Robin C Guy11 Analytical Toxic010gy(分析毒理学) 15
    Aneuploidy(非整倍性) 19
    Animal Models(动物模型) 22
    Aquatic Ecotoxicology(水域生态毒理学、水域生态毒物学) 24
    Aquatic Toxicity Testing(水生毒性试验) 24
    Avian Ecotoxicology(鸟类生态毒理学) 24
    Behavioral Toxicity Testing(行为中毒试验、行为毒性试验) 25
    Behavioral Toxicology(行为毒理学) 25
    Benchmark dose(基准剂量) 49
    Biological Exposure Index(生物照射) 52
    Biomarkers，Environmental(环境生物标记) 54
    Biomarkers，Human Health(人类健康生物标记) 57
    Biotransformation(生物转化) 62
    Carcinogen-DNA Adduct Formation and DNA Repair(致癌原-DNA加合物形成与DNA修复) 76
    Carcinogenesis(致癌作用) 8l
    Carcinogenicity Toxicity Testing(致癌毒性试验) 102
    Chemical—Specific Adjustment Factor(CSAF)(化学特异性调节因子) 103
    Chromosome Aberrations(染色体畸变、染色体异常) 106
    Combustion Toxicology(燃烧毒理学) 108
    Common Mechanism of Toxicity(主要毒性机理) 122
    Computational Toxicology(计算机毒理学) 124
    Cumulative Risk Assessment(累积危险评价) 128
    Deoxyribonucleic Acid(脱氧核糖核酸) 130
    Dermal Toxicity Testing(皮肤毒性试验) 130
    Development Toxicity Testing(发育毒性试验) 130
    Developmental Toxic010gy(发育毒理学) 130
    DNA(脱氧核糖核酸) 168
    DNA Adduct(DNA加合物) 168
    DNA Phosphoramidites(DNA亚磷酰胺) 168
    DNA Repair(DNA修复) 169
    Dominant Lethal Tests(显性致死试验) 170
    Dose-Response Relationship(剂量效应关系) 172
    Ecotoxicology(生态毒理学、生态毒物学) 176
    Ecotoxicology，Aquatic(水域生态毒理学) 180
    Ecotoxicology，Avian(鸟类生态毒理学) 18l
    Ecotoxicology，Genetic(遗传生态毒理学) 186
    Ecotoxicology，Invertebrate(无脊椎动物生态毒理学) 193
    Ecotoxic010gy，Terrestrial(陆地生物生态毒理学) 198
    Ecotoxicology，Wildlife(野生动植物生态毒理学) 203
    Environmental Hormone Disruptors(环境激素破坏剂) 207
    Environmental Toxicology(环境毒理学) 21l
    Exposure(暴露) 214
    Exposure Assessment[(危害)暴露评估] 217
    Exposure Criteria(暴露标准) 220
    Eye Irritancy Testing(眼球刺激试验) 225
    Food Safety and Toxicology(食品安全与毒理学) 233
    Foreign Body Response(异物反应) 239
    Forensic Toxic010gy(法医毒理学) 241
    Genetic Ecotoxicology(遗传生态毒理学) 247
    Genetic Toxicology(遗传毒理学) 248
    Genomics，Toxicogenomics(基因组、毒物基因组) 259
    Good Clinical Practice(GCP)(药物临床试验管理规范) 261
    Good Laboratory Practices(GLP)(良好实验室管理规范) 264
    Hormesis(毒物刺激作用) 268
    Hormone Disruptors(激素破坏剂) 271
    Host-Mediated Assay(宿主间介试验) 271
    Hypersensitivity，Delayed Type(迟发型超敏反应) 273
    Immediately Dangerous to Life or Health(1BLH)Values(即刻性损伤或致死浓度) 276
    Inhalation Testing(吸人试验) 278
    Interactions(相互作用) 278
    Interactive Toxicity(相互作用毒性) 278
    Irritation Testing(刺激试验) 283
    LD50／LC50(Lethal Dosage 50／Lethal Concentration 50)(半数致死剂量) 284
    Lethal，Dosage or Concentration(致死剂量／浓度) 288
    Levels of effect in Toxicological Assessment(毒物效应评价水平) 288
    Lowest-Observed-Adverse-Effect Level(观察到副作用的最小剂量) 290
    Lowest-Observed-Effect Level(观察到作用的最小剂量，最低作用水平) 290
    Margin of Exposure(MOE)(暴露界限) 290
    Maximum Allowable Concentration(MAC)(最高容许浓度) 291
    Maximum Tolerated Dose(MTD)(最大耐受剂量) 292
    Mechanisms of Toxicity(毒性机制) 293
    Mode of Action(作用方式) 297
    Models(模型) 298
    Modifying Factors of Toxicity(毒性修饰因子) 299
    Molecular Toxicology-Recombinant DNA Technology(分子毒理学-重组DNA技术) 306
    Mouse Lymphoma Assay(小鼠淋巴瘤测定) 314
    Neoplasia(瘤形成) 316
    Neurotoxicity(神经毒性) 316
    Nonionizing Radiation(非电离辐射) 328
    No-Observed-Adverse-Effect Level(未观察到的副作用水平) 328
    No—Observed—Effect Level(未观察到的效应水平) 328
    Occupational Exposure limits(职业性暴露极限) 329
    Occupational Toxicology(职业毒理学) 33l
    Ototoxicity(耳毒性) 339
    Pharmacokinetics／Toxicokinetics(药物代谢动力学／毒物代谢动力学) 343
    Pharmac010gy and Safety(安全药理学) 350
    Radiation Toxicology，Ionizing and Nonionizing(电离辐射与非电离辐射毒理学) 351
    Recombinant DNA(重组DNA) 365
    Safety Testing，Clinical Studies(临床研究安全试验) 366
    Sensitivity Analysis(灵敏度分析) 368
    Sensitization Testing(敏感试验、致敏试验) 369
    Short-Term Exposure limit(短期暴露限度) 369
    Subchronic Toxicity(亚慢性毒性) 369
    Terat010gy(畸形学) 369
    Teratology Testing(致畸实验) 369
    Terrestrial Ecotoxicology(陆地生态毒理学) 369
    Threshold Limit Value(阈限值) 369
    Toxicity Testing，Alternatives(选择性毒性试验) 370
    T0xicity Testing，Aquatic(水域毒性试验) 375
    Toxicity Testing，Behavioral(行为毒性试验) 382
    Toxicity Testing，Carcinogenesis(致癌毒性试验) 389
    T0xicity Testing，Dermal(皮肤毒性试验) 394
    Toxicity Testing，Developmental(发育毒性试验) 404
    Toxicity Testing，Inhalation(吸人毒性试验) 418
    Toxicity Testing，Irritation(刺激毒性试验) 428
    Toxicity Testing，Modeling(模型化毒性试验) 430
    Toxicity Testing，Mutagenicity(致突变毒性试验) 435
    Toxicity Testing，‘Read Across Analysis’ [识读交叉分析(毒性试验)]
    Toxicity Testing，Reproductive(生殖毒性试验)
    Toxicity Testing，Sensitization(致敏毒性试验)
    Toxicity Testing，Validation(毒性试验验证)
    Toxicity，Acute(急性毒性)
    Toxicity，Chronic(长期毒性)
    Toxicity，Subchronic(亚慢性毒性)
    Toxicokinetics(毒物代谢动力学)
    Toxic010gy(毒理学)
    Toxicology，Intuitive(直觉毒理学)
    Uncertainty Analysis(不确定检验)
    Uncertainty Factors(不确定系数)
    Validation of T0xicity Testing(毒性试验验证)
    Veterinary Toxic010gy(兽医毒理学) 502
    Virtually Safe Dose(VSD)(实际安全剂量) 516