首页 > 新书资源
新书资源(2008年9月)

Gene function analysis / edited by Michael F. Ochs. — Totowa, N.J. : Humana, c2007. – (58.17/M592/v.408)

Contents

        Contents
    
    Preface vii
    Contributors xiii
    PART I COMPUTATIONAL METHODS I
    1 Gene Function Inference From Gene Expression of Deletion Mutants
    2 Association Analysis for Large-Scale Gene Set Data
    3 Estimating Gene Function With Least Squares Nonnegative Matrix Factorization
    4 From Promoter Analysis to Transcriptional Regulatory Network Prediction Using PAINT
    5 Prediction of Intrinsic Disorder and Its Use in Functional Proteomics
    PART II COMPUTATIONAL METHODS II
    6 Sybil: Methods and Software for Multiple Genome Comparison and Visualization
    7 Estimating Protein Function Using Protein-Protein Relationships
    8 Bioinformatics Tools for Modeling Transcription Factor Target Genes and Epigenetic Changes
    9 Mining Biomedical Data Using MetaMap Transfer (MMTx) and the Unified Medical Language System (UMLS)
    10 Statistical Methods for Identifying Differentially Expressed Gene Combinations
    PART III EXPERIMENTAL METHODS
    11 Gene Function Analysis Using the Chicken B-Cell Line DT40
    12 Design and Application of a shRNA-Based Gene Replacement Retrovirus
    13 Construction of Simple and Efficient DNA Vector-Based Short Hairpin RNA Expression Systems for Specific Gene Silencing in Mammalian Cells
    14 Selection of Recombinant Antibodies From Antibody Gene Libraries
    15 A Bacterial/Yeast Merged Two-Hybrid System: Protocol for Yeast Screening With Single or Parallel Baits
    16 A Bacterial/Yeast Merged Two-Hybrid System: Protocol for Bacterial Screening
    17 Engineering Cys2His2 Zinc Finger Domains Using a Bacterial Cell-Based Two-Hybrid Selection System