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新书资源(2008年6月)

Target discovery and validation : reviews and protocols. v. 2, Emerging molecular targets and treatment options / edited by Mouldy Sioud. — Totowa, N.J. : Humana Press, c2007. – (58.17/M592/v.361)

Contents

    Contents
    
    Preface
    Contributors
    Contents of Volume 1
    1 Druggable Signaling Proteins
    2 DNA Methylation and Histone Modifications in Patients With Cancer: Potential Prognostic and Therapeutic Targets
    3 Wnt Signaling as a Therapeutic Target for Cancer
    4 The NG2/HMP Proteoglycan as a Cancer Therapeutic Target
    5 Heterotrimeric G Proteins and Disease
    6 High-Mobility Group Box-1 Isoforms as Potential Therapeutic Targets in Sepsis
    7 Antisense Oligonucleotides: Target Validation and Development of Systemically Delivered Therapeutic Nanoparticles
    8 Nucleic Acid-Based Aptamers as Promising Therapeutics in Neoplastic Diseases
    9 Guidelines for the Selection of Effective Short-Interfering RNA Sequences for Functional Genomics
    10 Suppression of Apoptosis in the Liver by Systemic and Local Delivery of Small-Interfering RNA
    11 Target Validation Using RNA Interference in Solid Tumors
    12 Validation of Telomerase and Survivin as Anticancer Therapeutic Targets Using Ribozymes and Small-Interfering RNAs
    13 Collagen-Induced Arthritis in Mice: A Major Role for Tumor Necrosis Factor-α
    14 Novel Opportunities for Therapeutic Targeting in Systemic Autoimmune Diseases
    15 Considerations for Target Validation and Industrial Approaches
    16 Regulatory RNAs: Future Perspectives in Diagnosis, Prognosis, and Individualized Therapy
    17 Treatment Options and Individualized Medicine
    Index 341