Engineering the human germline : an exploration of the science and ethics of altering the genes we pass to our children / edited by Gregory Stock and John Campbell. — New York ; Oxford : Oxford University Press, 2000.—(63.141/E57) |
Contents
Contents
Contributors xi
Introduction: An Evolutionary Perspective 3
Ⅰ THE REALITIES OF HUMAN GERMLINE ENGINEERING
A Vision for Practical Human Germline Engineering 9
John Campbell and Gregory Stock
The Human Genome Project--Launch Pad for Human Genetic Engineering 17
Leroy Hood
Ethics and Safety 25
Daniel Koshland, Jr.
Human Germline Gene Therapy: How and Why 31
Mario R. Capecchi
A New Front in the Battle against Disease 43
W. French Anderson
Aging as a Target for Genetic Engineering 49
Michael R. Rose
Reprogenetics: How Reproductive and Genetic Technologies Will Be Combined to Provide New Opportunities for People to Reach Their Reproductive Goals 57
Lee M. Silver
II THE ROAD AHEAD
A Panel Discussion 73
John Campbell, Leroy Hood, Daniel Koshland, Jr., Mario Capecchi, W. French Anderson, Michael R. Rose, Lee M. Silver, Andrea Bonnicksen, John Fletcher, and James D. Watson. Moderated by Gregory Stock.
III OTHER VOICES
Beyond the Issue of Safety 99
Glenn McGee, Sandy Thomas, Sheldon Krimsky, Kevin T. FitzGerald, Ruth Hubbard, Gregory E. Pence and Stefan E Winter
Long-Term Possibilities and Dangers 117
Alex Mauron, Rabbi Barry Freundel, Erik Parens, Burke K. Zimmerman, Paul R. Billings, James Hughes, George Ennenga, and Jan C. Heller
Regulation and Jurisdiction 139
Darryl Macer and Lloyd Cohen
Appendix: Select Questions from the Public to Participants in the "Engineering the Human Germline" Symposium 145
Notes 151
Glossary 159
Index 161