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Engineering the human germline : an exploration of the science and ethics of altering the genes we pass to our children / edited by Gregory Stock and John Campbell. — New York ; Oxford : Oxford University Press, 2000.—(63.141/E57)

Contents

    Contents
    
    Contributors xi
    Introduction: An Evolutionary Perspective 3
    Ⅰ THE REALITIES OF HUMAN GERMLINE ENGINEERING
    A Vision for Practical Human Germline Engineering 9
     John Campbell and Gregory Stock
    The Human Genome Project--Launch Pad for Human Genetic Engineering 17
     Leroy Hood
    Ethics and Safety 25
     Daniel Koshland, Jr.
    Human Germline Gene Therapy: How and Why 31
     Mario R. Capecchi
    A New Front in the Battle against Disease 43
     W. French Anderson
    Aging as a Target for Genetic Engineering 49
     Michael R. Rose
    Reprogenetics: How Reproductive and Genetic Technologies Will Be Combined to Provide New Opportunities for People to Reach Their Reproductive Goals 57
     Lee M. Silver
    II THE ROAD AHEAD
    A Panel Discussion 73
     John Campbell, Leroy Hood, Daniel Koshland, Jr., Mario Capecchi, W. French Anderson, Michael R. Rose, Lee M. Silver, Andrea Bonnicksen, John Fletcher, and James D. Watson. Moderated by Gregory Stock.
    III OTHER VOICES
    Beyond the Issue of Safety 99
     Glenn McGee, Sandy Thomas, Sheldon Krimsky, Kevin T. FitzGerald, Ruth Hubbard, Gregory E. Pence and Stefan E Winter
    Long-Term Possibilities and Dangers 117
     Alex Mauron, Rabbi Barry Freundel, Erik Parens, Burke K. Zimmerman, Paul R. Billings, James Hughes, George Ennenga, and Jan C. Heller
    Regulation and Jurisdiction 139
     Darryl Macer and Lloyd Cohen
    Appendix: Select Questions from the Public to Participants in the "Engineering the Human Germline" Symposium 145
    Notes 151
    Glossary 159
    Index 161