Chromatin dynamics in cellular function / Brehon C. Laurent (ed.). — Berlin : Springer, c2006. -- (58.1553/C557d)

Contents

            Contents
    
    Structure and Function of Protein Modules in Chromatin Biology
    1 Introduction
    2 Histone Lysine Acetylation Recognition by the Bromodomain
    3 Histone Lysine Methylation Recognition
    4 Chromosomal DNA/Histone Binding
    5 Chromosomal Protein-Protein Interactions
    6 Discussion
    7 Future Directions
    8 Concluding Remarks
    References
    The Generation and Recognition of Histone Methylation
    1 Introduction
    2 The Nucleosome and Chromatin Structure
    3 Histone Methylation
    4 Histone Modification Binding Proteins
    5 Histone Modification Crosstalk with Methylation
    6 Conclusions and Future Perspectives
    References
    Histone Ubiquitylation and the Regulation of Transcription
    1 Regulation of Histone Ubiquitylation
    2 Relationship Between Histone H2B Ubiquitylation and Histone H3 Methylation
    3 Role of Histone Ubiquitylation in Gene Expression.
    4 Additional Cellular Roles of Ubiquitylated Histones
    5 Summary and Perspectives
    References
    Histone Dynamics During Transcription: Exchange of H2A/H2B Dimers and H3/H4 Tetramers During Pol II Elongation
    1 A Brief History of Chromatin and Transcription
    2 RNA Polymerase Activity Induces Histone Exchange with Free Pools
    3 Histone Exchange May be Due to RNA Pol II Elongation Through Nucleosomes
    4 Exchange of H3/H4 Tetramers During Transcription
    5 H2A/H2B vs H3/H4 Exchange
    6 Perspectives
    References
    The Roles of Chromatin Remodelling Factors in Replication
    1 Introduction
    2 Histone Modifications and DNA Replication
    3 Histone Chaperones and DNA Replication
    4 ATP-Dependent Remodelling Factors and Chromatin Dynamics in DNA Replication
    5 Conclusion
    References
    Chromatin Modifications in DNA Repair
    1 Overview of Chromatin Modifications
    2 Histone Modifications in DNA Repair
    3 Chromatin-Modifying Complexes in DNA Repair
    4 Future Directions
    References
    Mechanisms for Nucleosome Movement by ATP-dependent Chromatin Remodeling Complexes
    1 Introduction
    2 Nucleosome Specialization
    3 The Nucleosome: A Biophysical Challenge for Remodelers
    4 Remodelers Resemble DNA Helicases/Translocases
    5 Chromatin Remodeling Enables Specialized Biological Functions
    6 Conclusion
    References
    Subject Index