Gene expression and regulation / Jun Ma, editor. — Beijing : Higher Education Press, c2006. – (58.1481/G326r)

Contents

        Contents
    About the Editor
    Preface
    Section I The History
    Chapter 01 Transcription: The Never Ending Story 3
    Section II The Machinery
    Chapter 02 The General Transcription Machinery and Preinitiation Complex Formation 21
    Chapter 03 The Dynamic Association of RNA Polymerase II with Initiation， Elongation， and RNA Processing Factors during the Transcription Cycle 49
    Chapter 04 General Cofactors: TFIID， Mediator and USA 67
    Chapter 05 Chromatin and Regulation of Gene Expression 95
    Chapter 06 HATs and HDACs 111
    Chapter 07 Structure and Function of Core Promoter Elements in RNA Polymerase II Transcription 135
    Section III The Regulators
    Chapter 08 Transcriptional Activators and Activation Mechanisms 147
    Chapter 09 Transcriptional Repressors and Repression Mechanisms 159
    Chapter 10 STATs in Cytokine-mediated Transcriptional Regulation 175
    Chapter 11 Transcriptional Regulation by Smads 185
    Chapter 12 The Rb and E2F Families of Proteins 207
    Chapter 13 c-Jun: A Complex Tale of a Simple Transcription Factor 219
    Chapter 14 HIV Tat and the Control of Transcriptional Elongation 239
    Chapter 15 Post-translational Modifications of the p53 Transcription Factor 257
    Chapter 16 Actions of Nuclear Receptors 273
    Chapter 17 NFAT and MEF2， Two Families of Calcium-dependent Transcription Regulators 293
    Chapter 18 Hox Genes 309
    Chapter 19 Nuclear Factor-kappa B 321
    Chapter 20 The ATF Transcription Factors in Cellular Adaptive Responses 329
    Section IV The Genome
    Chapter 21 Function and Mechanism of Chromatin Boundaries 343
    Chapter 22 Heterochromatin and X Inactivation 365
    Chapter 23 DNA Methylation Regulates Genomic Imprinting， X Inactivation， and Gene Expression during Mammalian Development 377
    Chapter 24 Comparative Genomics of Tissue Specific Gene Expression 393
    Chapter 25 Transcription and Genomic Integrity 409
    Chapter 26 Cell Death and Transcription 431
    Section V Special Topics
    Chapter 27 Pre-mRNA Splicing in Eukaryotic Cells 447
    Chapter 28 Genome Organization: The Effects of Transcription-driven DNA Supercoiling on Gene Expression Regulation 469
    Chapter 29 The Biogenesis and Function of MicroRNAs 481
    Chapter 30 Transcription Factor Dynamics 493
    Chapter 31 Actin， Actin-Related Proteins and Actin-Binding Proteins in Transcriptional Control 503
    Chapter 32 Wnt Signaling and Transcriptional Regulation 519
    Chapter 33 Regulatory Mechanisms for Floral Organ Identity Specification in Arabidopsis thaliana 533
    Chapter 34 Transcription Control in Bacteria 549
    Chapter 35 Gene Therapy: Back to the Basics 565