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Quinones and quinone enzymes. pt. B / edited by Helmut Sies, Lester Packer. -- (Methods in enzymology ; v. 382). -- Elsevier, 2004. -- (58.17435/C719/v.382/pt.B) |
Contents
Contents: 1. Mitochondrial Quinone Reductases: Complex I 3 2. Q-cycle Bypass Reactions at the Qo Site of the Cytochrome bc1 (and Related) Complexes 21 3. Targeting Coenzyme Q Derivatives to Mitochondria 45 4. The Mitochondrial Interplay of Ubiquinol and Nitric Oxide in Endotoxemia 67 5. Mitochondrial Respiratory Chain Dysfunction Caused by Coenzyme Q Deficiency 81 6. Coenzyme Q Cytoprotective Mechanisms 89 7. Dietary Coenzyme Q10 and Mitochondrial Status 105 8. NAD(P)H: Quinone Oxidoreductase 1 (NQo1, DT-Diaphorase), functions and Pharmacogenetics 115 9. Structure Mechanism of NAD[P]H: Quinone Acceptor Oxidoreductases (NQO) 144 10. Diaziridinylbenzoquinones 174 11. Quinone Reductase-Mediated Nitro-Reduction: Clinical Applications 194 12. Bioactivation and Resistance to Mitomycin C 221 13. NAD(P)H: Quinone Oxidoreductase 1 Expression, Hydrogen Peroxide Levels, and Growth Phase in Hela Cells 234 14. The "Prochaska" Microtiter Plate Bioassay for Inducers of NQO1 243 15. Structure-Activity Relationships in Two-Electron Reduction of Quinones 258 16. p53-Dependent apoptosis and NAD(P)H:Quinone Oxidoreductase 1 278 17. The Role of Endogenous Catechol Quinones in the Initiation of Cancer and Neurodegenerative Diseases 293 18. Induction of NQO1 in Cancer Cells 320 19. Role of Nicotinamide Quinone Oxidoreductase 1(NQO1) in Protection Against Toxicity of Electrophiles and Reactive Oxygen Intermediates 355 20. Activation and Detoxification of Naphthpquinones by NAD(P)H: Quinone Oxidoreductase 364 ... ... |
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