Molecular analysis and genome discovery / edited by Ralph Rapley and Stuart Harbron. -- John Wiley & Sons. -- 2004. -- 58.1481/M718g |
Contents
Contents:
1. Pharmacogenetics and Pharmacogenomics: An Overview 1
2. Quantitative TaqMan Real-time PCR: Diagnostic and Scientific Applications 17
3. Hybridization Probes for Real-time PCR 29
4. An Overview of Genotyping and Single Nucleotide Polymorphisms (SNP) 43
5. High-throughput Mutation Screening 71
6. Determination of Nucleic Acid Sequences by Pyrosequencing 101
7. An Introduction to DNA Chips 113
8. Overview of Microarrays in Genomic Analysis 127
9. Overview of Differential Gene Expression by High-throughput Analysis 167
10. Aptamers: Powerful Molecular Tools for Therapeutics and Diagnostics 191
11. Chip-based Proteomics Technology 217
12. Indectomics Overview: Holistic and Integrativs Studies of Infectious Diseases 251
13.The Drug Discover Process 271
14. Structure-based Drug Discovery 295
15. Protein Interaction-targeted Drug Discovery 323
16. Overview of Quantitative Structure-Activity Relationships (QSAR) 347