Biotechnology and Biopharmaceuticals / by Rodney J.Y. Ho and Milo Gibaldi. -- Wiley , 2003

1. Introduction to Biopharmaceuticals  3

2. Comparative Drug Development of Proteins and Genes versus Small Molecules  11

3. Biotechnology Industry Perspective on Drug Development  21

4. Biopharmaceutical Technologies and Processes in Drug Development  35

5. Pharmacology, Toxicology, therapeutic dosage Formulations, and Clinical Response  97

6. Hematopoietic Growth Factors and Coagulation Factors  127

7. Interferons and cytokines for Anti-infective and Cancer Therapy  161

8. Hormones  209

9. Enzymes  245

10. antibodies and Derivative  271

11. Vaccines  313

12. Other Products: Monographs  331

13. Advanced Drug Delivery  339

14. Individualization of Drug Ragimens: Integration of Pharmacokinetic and Pharmacogenetic Principles in Drug Therapy  381

15. Gene and Cell Therapy  401

16. Integration of discovery and Development: the Role of genomic and Proteomics  427